Burkholderia cepacia

Burkholderia cepacia and other Burkholderia species

Burkholderia cepacia (Genomovar I) (formerly Pseudomonas cepacia) is a bacterium found in approximately 5% of those with CF. Cepacia Syndrome is when someone infected with B. cepacia experiences rapid decline in health. There are 7 types of B. cepacia associated with Cepacia Syndrome. Cepacia Sepsis is when B. cepacia enters the bloodstream. 82% of B. cepacia strains have no effective synergistic antibiotic combination available. Some types of bacteria, once resistant, seldom return to a sensitive state. B. cepacia is one such bacterium, which seldom loses its resistant nature. B. cepacia survives on the skin for up to 60 minutes, on a moist surface for up to one week, and in water for years. This makes indirect spread possible. Since B. cepacia broke out in the 80's, segregation and strict hygiene has helped in limiting it's spread.
- Agricultural Use of Burkholderia (Pseudomonas) cepacia: A Threat to Human Health? (Added Jan. 14, 1999)
- Burkholderia cepacia Risk Assessment of a Biopesticide with Affinities to a Human Opportunistic Pathogen (Link updated Nov. 22, 2006)
- Multiple Combination Bactericidal Antibiotic Testing for Patients with Cystic Fibrosis Infected with Burkholderia cepacia (Added Oct. 18, 2000)
- Misidentification of Burkholderia cepacia in US Cystic Fibrosis Treatment Centers (Added Aug. 14, 2001)
- Epidemiology of Burkholderia cepacia Complex in Patients with Cystic Fibrosis, Canada (Link updated Aug. 25, 2004)
- Burkholderia cepacia complex in cystic fibrosis and non-cystic fibrosis patients: identification of a cluster of epidemic lineages (Italy) (Link updated Aug. 25, 2004)
- Synergistic Activities of Macrolide Antibiotics against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans Isolated from Patients with Cystic Fibrosis (Added Mar. 18, 2002)
- Differential Persistence among Genomovars of the Burkholderia cepacia Complex in a Murine Model of Pulmonary Infection (Added Apr. 30, 2002)
- Effect of Burkholderia cepacia infection in the clinical course of patients with cystic fibrosis: A pilot study in a Sydney clinic (Link updated Jan. 14, 2008)
- Advances in Burkholderia cepacia complex (Link updated Aug. 25, 2004)
- Risk factors for Burkholderia cepacia complex colonization and infection among patients with cystic fibrosis (Added Oct. 21, 2002)
- Burkholderia cepacia Complex in Cystic Fibrosis: Frequency of Strain Replacement during Chronic Infection (Link updated Jan. 5, 2008)
- Burkholderia cepacia and cystic fibrosis Discusses the 9 genomovar types (Added Aug. 19, 2004)
- Clinical outcome of Burkholderia cepacia complex infection in cystic fibrosis adults (Link updated Jan. 14, 2008)
- Burkholderia cepacia Is Associated with Pulmonary Hypertension and Increased Mortality among Cystic Fibrosis Patients (Added Dec. 11, 2004)
- Organisms isolated from adults with Cystic Fibrosis (Added Dec. 29, 2004)
- Burkholderia cepacia: Pandora’s box redefined (Link updated Mar. 13, 2006)
- Infection with Burkholderia cepacia in Cystic Fibrosis: Outcome Following Lung Transplantation (Added Apr. 27, 2005)
- Laboratory Aspects of Management of Chronic Pulmonary Infections in Patients with Cystic Fibrosis (Added Apr. 27, 2005)
- Combination aerosol therapy to treat Burkholderia cepacia complex (Added Aug. 30, 2005)
- Update on the Burkholderia cepacia complex (Link updated Jan. 14, 2008)
- The changing epidemiology of Burkholderia species infection at an adult cystic fibrosis centre (Added Sept. 17, 2008)
- Impact of Burkholderia Infection on Lung Transplantation in Cystic Fibrosis (Added Mar. 23, 2009)
Burkholderia multivorans (Genomovar II)
- ‘Cepacia syndrome’ with Burkholderia multivorans, 9 years after initial colonization (Link updated Jan. 14, 2008)
- Impact of Burkholderia dolosa on Lung Function and Survival in Cystic Fibrosis (Added Apr. 5, 2006)
- Impact of Burkholderia Infection on Lung Transplantation in Cystic Fibrosis (Added Mar. 23, 2009)
Burkholderia cenocepacia (formerly genomovar III of the Burkholderia cepacia complex)
- Widespread clone of Burkholderia cenocepacia in cystic fibrosis patients in the Czech Republic (Added Nov. 4, 2005)
- Burkholderia respiratory tract infections in Italian patients with cystic fibrosis: Molecular characterization (Added Oct. 5, 2006)
- Infection With Burkholderia cepacia Complex Bacteria and Pulmonary Exacerbations of Cystic Fibrosis (Added Apr. 23, 2007)
- Successful treatment of cepacia syndrome with combination nebulised and intravenous antibiotic therapy (Added Sept. 17, 2008)
- Impact of Burkholderia Infection on Lung Transplantation in Cystic Fibrosis (Added Mar. 23, 2009)
Burkholderia dolosa

(Genomovar VI)

This is a relatively new bug in people with CF. (Added Dec. 20, 2003)
Evidence of transmission of Burkholderia cepacia, Burkholderia multivorans and Burkholderia dolosa among persons with cystic fibrosis (Added Dec. 20, 2003)
Proposal to accommodate Burkholderia cepacia genomovar VI as Burkholderia dolosa sp. nov. (Added Jan. 8, 2006)
Children's Hospital Fights New Bacteria Strain (Added Jan. 8, 2006)
Impact of Burkholderia dolosa on Lung Function and Survival in Cystic Fibrosis (Added Apr. 5, 2006)

Burkholderia pseudomallei

Burkholderia pseudomallei: another emerging pathogen in cystic fibrosis (Added Dec. 22, 2003)

Burkholderia gladioli
- Burkholderia respiratory tract infections in Italian patients with cystic fibrosis: Molecular characterization (Added Oct. 5, 2006)
- Burkholderia gladioli: Five year experience in a cystic fibrosis and lung transplantation center (Added July 31, 2007)
- Impact of Burkholderia Infection on Lung Transplantation in Cystic Fibrosis (Added Mar. 23, 2009)

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